Circular RNA circCCNB1 inhibits the migration and invasion of nasopharyngeal carcinoma through binding and stabilizing TJP1 mRNA - EurekAlert
In a paper published in Science china life science, a team of scientists reveals a novel biological function of circCCNB1 in the migration and invasion of NPC by enhancing the tight junctions of cancer cells by binding to NF90 proteins and TJP1 mRNA, and may …
image: There are two forms of circRNAs (circCCNB1 and circCcnb1) derived by CCNB1 pre-mRNA. circCcnb1 (342 nt) is composed by exon 4 and 5 while circCCNB1 (378 nt) is formed by exon 6 and 7. Sanger s… [+3535 chars]
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